gene 691 words KG: SLC31A2
Contents

SLC31A2 — Solute Carrier Family 3 Member 1A2 (SLC31A2)

🧬 Gene Info
Gene SymbolSLC31A2
Full NameSolute Carrier Family 3 Member 1A2 (SLC31A2)
Chromosome9q32
Primary Expressionvarious tissues and plays complementary roles in copper acquisition, particularly in tissues where CTR1 expression is low or under conditions of high
UniProt IDO15432
NCBI Gene ID10552
Ensembl IDENSG00000137573
OMIM603086
GeneCardsSLC31A2
Human Protein AtlasSLC31A2
CTR1Dominates copper uptake at low extracellular copper concentrations
CTR2Becomes more important when copper concentrations are elevated [@affinity]
Associated DiseasesAls, Atherosclerosis
KG Connections8 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

SASP-Mediated Complement Cascade Amplification
Score: 0.82

Related Analyses (2)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (8)

Proposed experiment from debate on Synaptic pruning by micro
falsification · proposed · Score: 0.40
Proposed experiment from debate on Senolytics targeting p16/
falsification · proposed · Score: 0.40
Mechanism: Why Does Amyloid Removal Only Slow Decline 27%?
clinical · proposed · Score: 0.40
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.40
ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (8)

Neurodegeneration
disease · KG edge: implicated_in
cdkn2a
gene · KG edge: regulates
GLS - Glutaminase
gene · KG edge: regulates
RAB23 Gene
gene · KG edge: associated_with
SGCE — Sarcoglycan Epsilon
gene · KG edge: associated_with

Knowledge Graph (8 edges)

SGCE associated_with SLC31A2
NLRP3 regulates SLC31A2
SLC31A2 associated_with RAB23
SLC31A2 regulates CDKN2A
SLC31A2 regulates GLS
SLC31A2 associated_with Als
SLC31A2 associated_with Atherosclerosis
SLC31A2 associated_with Actin

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