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gene 975 words KG: SUZ12
Contents

SUZ12

🧬 Gene Info
Gene SymbolSUZ12
Full NameSUZ12 Polycomb Repressive Complex 2 Subunit
Chromosome17q11.2
Functionencodes an essential zinc finger-containing subunit of Polycomb Repressive Complex 2 (PRC2).
Amino Acids739 aa
PathwaysMtor
UniProt IDQ15022
Ensembl IDENSG00000178691
OMIM606245
GeneCardsSUZ12
Human Protein AtlasSUZ12
Associated Diseasesneurodegeneration
KG Connections8 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (2)

APOE-Dependent Autophagy Restoration
Score: 0.89Blocking AGE-RAGE Signaling in Enteric Glia to Prevent Neuro
Score: 0.61

Related Analyses (2)

Mechanistic role of APOE in neurodegeneration
neurodegeneration · archivedCircuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (4)

Epigenetic Dysregulation Validation in Parkinson's Disease
clinical · proposed · Score: 0.40Levodopa-Induced Dyskinesias Mechanism — Experiment Design
validation · proposed · Score: 0.40Non-Motor Symptom Progression in Parkinson's Disease — Mecha
clinical · proposed · Score: 0.40Spinocerebellar Ataxia (SCA) Disease-Modifying Therapy Devel
validation · proposed · Score: 0.40

See Also (6)

Neurodegeneration
disease · KG edge: implicated_inmTOR Signaling Dysregulation in Progressive Supranuclea
event · KG edge: regulatesDNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: regulatesMTOR Gene
gene · KG edge: regulatesPI3K — Phosphoinositide 3-Kinase
gene · KG edge: regulates

Knowledge Graph (8 edges)

PI3K regulates SUZ12
AKT regulates SUZ12
SUZ12 regulates MTOR
CANCER regulates SUZ12
DNA regulates SUZ12
SUZ12 regulates Cancer
SUZ12 regulates Als
SUZ12 regulates Mtor

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