gene 2,365 words KG: UBQLN1
Contents

UBQLN1 — Ubiquilin 1

🧬 Gene Info
Gene SymbolUBQLN1
Full NameUbiquilin 1
Chromosome9q21.33
Functionis a gene located on chromosome 9q21.
Molecular Weight62.5 kDa
Amino Acids589 aa
PathwaysAutophagy
UniProt ID[Q9UMX0](https://www.uniprot.org/uniprot/Q9UMX0)
Ensembl IDENSG00000135185
GeneCardsUBQLN1
Human Protein AtlasUBQLN1
Associated Diseasesneurodegeneration
InteractionsAUTOPHAGY
KG Connections5 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (12)

Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.54
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.53
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.51

Related Analyses (7)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Gene expression changes in aging mouse brain predicting neur
neurodegeneration · archived

See Also (15)

UPenn Observational Research Repository (NCT04715399)
clinical · Pages share 9 hypotheses
remternetug-anti-amyloid-alzheimers
clinical_trial · Pages share 9 hypotheses
nct05508789
clinical_trial · Pages share 9 hypotheses
LX1001 Long-Term Follow-up (NCT05400330) - Gene Therapy
clinical · Pages share 9 hypotheses
LX1001 Phase 1/2 Trial (NCT03634007) - Gene Therapy for
clinical · Pages share 9 hypotheses

Knowledge Graph (5 edges)

UBQLN1 regulates CD36
UBQLN1 activates Atherosclerosis
UBQLN1 activates Autophagy
UBQLN1 activates AUTOPHAGY
CD36 regulates UBQLN1