gene 806 words KG: WNT3A 2026-03-22
kind:genesection:genesstate:published
Contents

WNT3A Gene

🧬 Gene Info
Gene SymbolWNT3A
Chromosome17q21.31
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight36 kDa
Amino Acids352 aa
Exons4
PathwaysWnt, WNT
NCBI Gene ID89780
Ensembl IDENSG00000134245
GeneCardsWNT3A
Human Protein AtlasWNT3A
ReceptorAffinity
FZD1High
FZD5High
FZD7Moderate
Associated Diseasesneurodegeneration
InteractionsP38, DKK-1, LRP6, CACNA1G, RANK, CANCER
KG Connections105 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Knowledge Graph

Related Hypotheses (6)

Inhibitory Neuron-Selective WNT Signaling Restoration
Score: 0.39
CYP46A1 Overexpression Gene Therapy
Score: 0.63
Sleep Spindle-Synaptic Plasticity Enhancement
Score: 0.49
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.48
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45

Related Analyses (6)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (9)

Packard Center for ALS Research
institution · KG edge: activates
Alzheimer Indonesia
institution · KG edge: inhibits
LRP6 Gene
gene · KG edge: co_discussed
LEF1
gene · KG edge: activates
KLF14 Gene
gene · KG edge: inhibits

Knowledge Graph (12 edges)

WNT3A activates P38
WNT3A activates DKK-1
WNT3A therapeutic_target LRP6
WNT3A inhibits LRP6
WNT3A activates CACNA1G
WNT3A activates RANK
WNT3A activates Osteoclast
WNT3A expressed_in thalamus
WNT3A activates WNT PATHWAY
WNT3A expressed_in WNT5A