gene 2,609 words KG: ZFP36L2 2026-03-28
kind:genesection:genesstate:published
Contents

ZFP36L2 — Zinc Finger Protein L2

🧬 Gene Info
Gene SymbolZFP36L2
Full NameZinc Finger Protein Like 2
Chromosome12p13.31
Functionis a member of the ZFP36 family of zinc finger proteins.
Subcellular Localizations, and potentially different target RNA specificity. Some isoforms lack certain regulatory domains, which may affect the
Molecular Weight54 kDa
Amino Acids490 aa
PathwaysApoptosis
GeneCardsZFP36L2
Human Protein AtlasZFP36L2
CCR4-NOTDirect
EXOSC10Direct
G3BP1Functional
CNOT1Direct
ZFP36L1Redundant
Associated DiseasesALS
KG Connections14 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (13)

Liquid-Liquid Phase Separation Modifier Therapy
Score: 0.42
Chromatin Accessibility Restoration via BRD4 Modulation
Score: 0.56
Phase-Separated Organelle Targeting
Score: 0.52
Epigenetic Memory Erasure via TET2 Activation
Score: 0.52
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51

Related Analyses (5)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (7)

Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: regulates
IL12B Gene - Interleukin 12 Beta
gene · KG edge: expressed_in
BCL2 Gene
gene · KG edge: regulates
Tumor Necrosis Factor (TNF)
entity · KG edge: expressed_in
TNF (Redirect)
redirect · KG edge: expressed_in

Knowledge Graph (12 edges)

ZFP36L2 expressed_in IL12B
ZFP36L2 regulates TNF
ZFP36L2 associated_with ZFP36
ZFP36L2 expressed_in Ms
ZFP36L2 expressed_in Tumor
ZFP36L2 regulates APOPTOSIS
ZFP36L2 regulates Leukemia
ZFP36L2 regulates Apoptosis
ZFP36L2 associated_with ALS
ZFP36L2 regulates Immune Response