| Gene Symbol | ent-gene-95250f02 |
| Primary Expression | cGAS and STING are expressed in microglia, astrocytes, and at lower levels in neurons; upregulated in disease states |
| Subcellular Localization | cGAS is cytoplasmic (senses dsDNA); STING resides at the ER membrane and traffics to Golgi upon activation |
| Primary Target | STING (TMEM173) palmitoylation site or trafficking domain; or cGAS catalytic domain |
| Target Type | Small-molecule STING inhibitor (H-151 class) or cGAS inhibitor (RU.521 class) |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |