gene 3,150 words KG: IL1RAP
Contents

IL1RAP — Interleukin-1 receptor accessory protein

🧬 Gene Info
Gene SymbolIL1RAP
Full NameInterleukin-1 receptor accessory protein
Chromosome3q28
Protein TypeReceptor
Functionis a critical coreceptor for the interleukin-1 receptor family, essential for IL-1 signaling cascade activation.
Primary ExpressionMicroglia, Astrocytes, Spleen, Liver, Bone Marrow
Amino Acids570 aa
Exons12
UniProt IDQ9NPH8
NCBI Gene ID3556
Ensembl IDENSG00000124788
OMIM602463
GeneCardsIL1RAP
Human Protein AtlasIL1RAP
Extracellular domainThree immunoglobulin-like domains responsible for ligand binding and interaction with IL1R1/IL1R2
Associated DiseasesAlzheimer's Disease, Multiple Sclerosis, Glioma
DatabasesGeneCardsHPASTRING

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NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (7 edges)

APOE expressed_in IL1RAP
CD33 expressed_in IL1RAP
GRN expressed_in IL1RAP
IL1RAP expressed_in TREM2
IL1RAP expressed_in microglia
IL1RAP data_in benchmark_ot_ad_answer_key:IL1RAP
benchmark_ot_ad_answer_key:IL1RAP data_in IL1RAP

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