gene 961 words KG: KANSL1
Contents

KANSL1 — KAT8 Regulatory NSL Complex Subunit 1

🧬 Gene Info
Gene SymbolKANSL1
Full NameKAT8 Regulatory NSL Complex Subunit 1
Chromosome17q21.31
FunctionThe complex acetylates histone H4K16, a modification critical for chromatin decompaction and transcriptional activation[@cai2010].
Primary Expressionthe adult brain with highest levels in the cortex (particularly frontal and temporal lobes)
Molecular Weight121 kDa
Amino Acids105 aa
Exons16
PathwaysMitophagy
UniProt IDQ7Z3B3
NCBI Gene ID284058
Ensembl IDENSG00000120071
OMIM612452
GeneCardsKANSL1
Human Protein AtlasKANSL1
Associated DiseasesAlzheimer's disease, Neurodegeneration, Parkinson
InteractionsAPOE, MAPT
KG Connections21 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

PINK1 regulates KANSL1
KANSL1 regulates KAT8
KANSL1 associated_with MAPT
KAT8 regulates KANSL1
STX17 regulates KANSL1
APOE interacts_with KANSL1
KANSL1 interacts_with MAPT
MITOPHAGY regulates KANSL1
NEURODEGENERATION implicated_in KANSL1
PARKINSON'S DISEASE associated_with KANSL1

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