gene 1,010 words KG: LRP6
Contents

LRP6 Gene

🧬 Gene Info
Gene SymbolLRP6
Chromosome12p13.2
Protein TypeReceptor
FunctionWnt ligand binds to LRP6 extracellular domain
Molecular Weight180 kDa
Pathwayssignaling: **Canonical Pathway Activation:**, Wnt, Wnt signaling
UniProt IDO75151
NCBI Gene ID4040
Ensembl IDENSG00000170054
GeneCardsLRP6
Human Protein AtlasLRP6
Associated DiseasesALS
InteractionsAKT, AKT1, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, APP
KG Connections97 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

LRP5 associated_with LRP6
LRP6 associated_with LDLR
LRP6 protects_against cardiac hypertrophy
LRP6 interacts_with HSP90α
LRP6 interacts_with CTSD
LRP6 activates CTSD
LRP6 associated_with LRP5
CTSD inhibits LRP6
LRP6 contributes_to APOB
DVL1 interacts_with LRP6

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