gene 820 words KG: MATRIN3 2026-03-21
kind:genesection:genesstate:published
Contents

MATR3 Gene

🧬 Gene Info
Gene SymbolMATR3
Full NameMatrin 3
AliasesMATA3, ATMR1
Chromosome5q31.2
FunctionMatr3 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
Subcellular LocalizationSignals (NLS)**: Two NLS sequences for nuclear import - **C-terminal domain**: M
Molecular Weight125 kDa
Amino Acids847 aa
PathwaysAutophagy, Proteasome, Dna Repair, autophagy pathway
UniProt IDP43243
NCBI Gene ID9782
Ensembl IDENSG00000015479
GeneCardsMATR3
Human Protein AtlasMATR3
Associated DiseasesALS, Amyotrophic Lateral Sclerosis, Dementia, Frontotemporal Dementia, Multisystem Proteinopathy
InteractionsRANK, NEURODEGENERATION, MOTOR NEURONS, AUTOPHAGY, AMYOTROPHIC LATERAL SCLEROSIS, GAIN
KG Connections143 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Knowledge Graph (12 edges)

MATRIN3 associated_with ALS
MATRIN3 regulates Amyotrophic Lateral Sclerosis
MATRIN3 regulates Aging
MATRIN3 regulates Proteasome
MATRIN3 associated_with Tdp-43
MATRIN3 regulates Autophagy
MATRIN3 regulates Ubiquitin-Proteasome
MATRIN3 expressed_in Neuron
UBIQUITIN regulates MATRIN3
HSP90 regulates MATRIN3