| Gene Symbol | ARSAPROTEIN |
| Full Name | Arylsulfatase A |
| Protein Family | Arylsulfatase family |
| Protein Type | Hydrolase |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 54 kDa (511 amino acids) |
| Amino Acids | 511 aa |
| UniProt ID | P15289 |
| GeneCards | ARSAPROTEIN |
| Human Protein Atlas | ARSAPROTEIN |
| Formylglycine (FGly) cofactor | Generated by the formylglycine-generating enzyme (FGE) at a conserved cysteine motif (C/S-X-P-X-R) |
| Active site | FGly coordinates sulfate ester hydrolysis |
| Homodimer formation | Two ARSA subunits associate for optimal activity |
| Glycosylation | N-linked glycans target the enzyme to lysosomes |
| Associated Diseases | neurodegeneration |
| Interactions | AGING, AUTOPHAGY, CCL2, CCL3, CTSD, CXCL12 |
| KG Connections | 27 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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