| Gene Symbol | CASP3 |
| Full Name | Caspase-3 (CASP3) |
| Aliases | CASPASE3PROTEIN |
| Chromosome | 4q35.1. |
| Protein Family | Cysteine-aspartate protease (caspase) family |
| Protein Type | Protein |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | Cytoplasm, mitochondria (activated) |
| Molecular Weight | 32 kDa (zymogen); 17 + 12 kDa (active heterodimer) |
| Pathways | Apoptosis |
| UniProt ID | P42574 |
| GeneCards | CASP3 |
| Human Protein Atlas | CASP3 |
| Disease | Primary Trigger |
| ALS | SOD1, TDP-43 |
| Associated Diseases | Lymphoma |
| Interactions | JUN, HSP90AA1, AKT1, FOXO1, PIK3CG, PI3K |
| KG Connections | 220 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |