protein 653 words KG: CRY2PROTEIN
Contents

CRY2 Protein

🔬 Protein Info
Gene SymbolCRY2
Full NameCryptochrome Circadian Regulator 2
Chromosome4p16.3
FunctionThe CRY2 gene encodes Cryptochrome Circadian Regulator 2, a key component of the mammalian circadian clock.
Subcellular Localization</strong></td><td>Nucleus, Cytoplasm</td></tr>
Molecular Weight66 kDa
PathwaysAmyloid, Cholesterol, Circadian Rhythm, Lipid Metabolism, Mtor
UniProt IDQ96T44
NCBI Gene ID1399
Ensembl IDENSG00000116771
OMIM604961
GeneCardsCRY2
Human Protein AtlasCRY2
FAD cofactorEssential for cryptochrome function
Rossmann foldCharacteristic of FAD-binding proteins
Associated DiseasesAls, Depression, magnetoreception, Stroke
InteractionsActin, AKT, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, APP
KG Connections113 knowledge graph edges
DatabasesGeneCardsHPASTRING

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UniProtWikipedia

Related Hypotheses (8)

Circadian Rhythm Entrainment of Reactive Astrocytes
Score: 0.72
HDAC3-Selective Inhibition for Clock Reset
Score: 0.71
Circadian Clock-Autophagy Synchronization
Score: 0.76
Circadian-Synchronized Proteostasis Enhancement
Score: 0.74
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
Temporal Decoupling via Circadian Clock Reset
Score: 0.54

Related Analyses (8)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (2)

Circadian gene expression effects of SD vs ketamine
exploratory · proposed · Score: 0.95
CLOCK/BMAL1 regulation of ICC autophagy in GERD model
exploratory · proposed · Score: 0.90

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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