| Gene Symbol | DNAJC12 |
| Aliases | DNAJC12PROTEIN |
| Chromosome | 10q22.1. |
| Protein Type | Chaperone |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 34.2 kDa |
| Amino Acids | 305 aa |
| Ensembl ID | ENSG00000156026 |
| GeneCards | DNAJC12 |
| Human Protein Atlas | DNAJC12 |
| Brain regions | High expression in cerebral cortex, hippocampus (CA1-CA3 pyramidal neurons), cerebellar cortex, basal ganglia, and brainstem nuclei |
| Peripheral tissues | Moderate expression in liver, kidney, pancreas, and testis |
| Cellular compartments | Primarily cytosolic, with partial ER and mitochondrial localization |
| Developmental regulation | Expression increases during neuronal maturation and differentiation |
| Associated Diseases | neurodegeneration |
| Interactions | AKT, APOPTOSIS, Caspase, FERROPTOSIS, GPX4, HSP70 |
| KG Connections | 12 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!