protein 727 words KG: ELMO1PROTEIN
Contents

ELMO1 Protein - Engulfment and Cell Motility 1

🔬 Protein Info
Gene SymbolELMO1
Full NameEngulfment and Cell Motility 1
AliasesPage for ELMO1, Page for ELMO1 Protein
Chromosome7p14.3
FunctionApoptotic Cell Clearance: ELMO1 mediates the recognition and engulfment of apoptotic cells by phagocytes [2]
Primary ExpressionMicroglia, Macrophages, Brain, Immune cells
Molecular Weight~85 kDa
PathwaysAutophagy
UniProt IDQ9Y6I4
NCBI Gene ID2004
Ensembl IDENSG00000126603
OMIM606520
GeneCardsELMO1
Human Protein AtlasELMO1
StructureMultiple domains mediating protein-protein interactions
Associated DiseasesParkinson's Disease, Alzheimer's Disease, Amyotrophic Lateral Sclerosis
InteractionsAUTOPHAGY, LC3, LC3B
KG Connections12 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Related Hypotheses (12)

Purinergic Signaling Polarization Control
Score: 0.71
Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.67
Senescent Cell Mitochondrial DNA Release
Score: 0.74
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Synaptic Phosphatidylserine Masking via Annexin A1 Mimetics
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.53

Related Analyses (10)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
Alpha-Synuclein Seeding Assays (RT-QuIC and PMCA)
biomarker · Pages share 3 hypotheses
IL-6 (Interleukin-6) in Neurodegeneration
biomarker · Pages share 3 hypotheses
Cell-Free DNA Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypotheses
Exosomal Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypotheses

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