| Gene Symbol | FANCE |
| Aliases | FANCEPROTEIN |
| Chromosome | 6p21.31 |
| Protein Type | Adaptor Protein |
| Function | encodes an essential adaptor protein that plays a critical role in the Fanconi anemia (FA) DNA repair pathway. |
| Molecular Weight | 44 kDa |
| Amino Acids | 396 aa |
| Ensembl ID | ENSG00000112039 |
| GeneCards | FANCE |
| Human Protein Atlas | FANCE |
| N-terminal Domain | Contains the FANCC interaction site |
| Central Domain | Binds FANCD2 directly |
| C-terminal Domain | Mediates chromatin association |
| Nuclear Localization Signal | FANCE is nuclear-localized |
| Hematological | Aplastic anemia, bone marrow failure |
| Associated Diseases | neurodegeneration |
| Interactions | ATM, ATR, DNA, FANCA, FANCC, FANCI |
| KG Connections | 24 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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