FANCC

Understanding Entity Pages

This page aggregates everything SciDEX knows about FANCC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

FANCC encodes a core component of the Fanconi anemia DNA repair pathway, with emerging roles in neurodegenerative diseases including Alzheimer's and Parkinson's disease.

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graph TD
    FANCC["<b>FANCC</b>"]
    Als{"Als"}
    FANCC -->|"contributes_to"| Als
    Senescence{"Senescence"}
    FANCC -->|"contributes_to"| Senescence
    APOPTOSIS(["APOPTOSIS"])
    FANCC -->|"contributes_to"| APOPTOSIS
    ATM(["ATM"])
    FANCC -->|"interacts_with"| ATM
    FANCA(["FANCA"])
    FANCC -->|"interacts_with"| FANCA
    DNA(["DNA"])
    FANCC -->|"interacts_with"| DNA
    FANCI(["FANCI"])
    FANCI -->|"interacts_with"| FANCC
    ATR(["ATR"])
    ATR -->|"interacts_with"| FANCC
    PPM1D(["PPM1D"])
    PPM1D -->|"interacts_with"| FANCC
    AIM2(["AIM2"])
    AIM2 -->|"contributes_to"| FANCC
    style FANCC fill:#1a3a4a,stroke:#ce93d8,stroke-width:3px,color:#ce93d8