protein 1,002 words KG: FXNPROTEIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

FXN Protein (Frataxin)

🔬 Protein Info
Gene SymbolFXN
AliasesFrataxin
Chromosome9q21.11
FunctionWithin this complex, frataxin
Primary ExpressionDorsal root ganglia, Spinal cord, Cerebellum, Heart, Pancreas, Liver
Subcellular Localization** Mitochondrial matrix (inner mitochondrial membrane)
Molecular Weight14 kDa
Amino Acids210 aa
PathwaysAutophagy, Mitophagy
UniProt IDQ16595
Ensembl IDENSG00000165060
OMIM606829
GeneCardsFXN
Human Protein AtlasFXN
GAA repeat expansionForms DNA triple helix and R-loop, blocking transcription elongation
Associated DiseasesAtaxia, Friedreich's Ataxia, Migraine
InteractionsMITOCHONDRIA, C-MYC, AND, MYC, HMOX1, TFAM
KG Connections63 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph