protein 3,096 words KG: GDI2PROTEIN 2026-03-26
kind:proteinsection:proteinsstate:publishedtopic:alzheimerstopic:parkinsons
Contents

GDI2 Protein

🔬 Protein Info
Gene SymbolGDI2
Full NameGDP Dissociation Inhibitor 2
AliasesGDI2PROTEIN
Chromosome10p15.3
Functionis a critical regulatory protein that controls the cycling of RAB GTPases between their active GTP-bound and inactive GDP-bound states[@pfeffer1996].
Primary ExpressionUbiquitous, high in brain
Subcellular LocalizationCytosol and associated with various membrane compartments
Molecular Weight51 kDa
Amino Acids467 aa
Exons13
UniProt ID[P50395](https://www.uniprot.org/uniprot/P50395)
Ensembl IDENSG00000123136
OMIM602134
GeneCardsGDI2
Human Protein AtlasGDI2
Associated DiseasesALS, Alzheimer
Known Drugs/Compoundsaducanumab
InteractionsCAPZB, NDUFS7, NDUFA4, Proteins, PLCB1, CD81
KG Connections37 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph