| Gene Symbol | HDAC7 |
| Aliases | HDAC7PROTEIN |
| Chromosome | 12q13 |
| Protein Type | Gene |
| Function | is a Class IIa histone deacetylase that plays crucial roles in gene regulation, cellular signaling, and neuronal function. |
| Subcellular Localization | </th><td>Nucleus/Cytoplasm (dynamic)</td></tr> [@hernandez2014] |
| Molecular Weight | 103 kDa |
| Amino Acids | 669 aa |
| Pathways | Oxidative Stress |
| GeneCards | HDAC7 |
| Human Protein Atlas | HDAC7 |
| Mef2-binding domain | Binds myocyte enhancer factor-2 transcription factors |
| 14-3-3 binding sites | Serine phosphorylation sites that mediate nuclear export |
| Scaffold interaction domains | Regions that recruit chromatin-modifying complexes |
| Zn²⁺-binding site | Essential for structural integrity |
| Associated Diseases | ALS, Cell Transformation, Tumor |
| Interactions | AKT, ALS, AMPK, AND, ATM, AXIN1 |
| KG Connections | 135 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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