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protein 667 words KG: LIG4PROTEIN
Contents

DNA Ligase IV Protein

🔬 Protein Info
Gene SymbolLIG4PROTEIN
Chromosome13q33
Functionis an important component in the neurobiology of neurodegenerative diseases.
Subcellular Localizationsome tumors ## Therapeutic Targeting **Therapeutic approaches:** - **Gene the
Molecular Weight100 kDa
GeneCardsLIG4PROTEIN
Human Protein AtlasLIG4PROTEIN
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

UniProtWikipedia

Related Hypotheses (3)

Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (9)

Epigenetic reprogramming in aging neurons
neurodegeneration · completedWhat determines the specificity of DDR protein recruitment t
neurodegeneration · completedHow do dilncRNAs specifically drive molecular crowding and p
neurodegeneration · completedMitochondrial transfer between astrocytes and neurons
neurodegeneration · archivedTDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived

Related Experiments (30)

Single-cell RNA-seq analysis of mouse testes with gonadal de
exploratory · completed · Score: 0.95GWAS of plasma pTau217 in East Asian cohort
exploratory · proposed · Score: 0.95cGAS/STING pathway activation by TDP-43-released mtDNA
exploratory · proposed · Score: 0.95IRF1 transcriptional regulation of Nlrc5 and Ciita promoters
exploratory · proposed · Score: 0.90Epigenetic clocks association with brain aging patterns in o
exploratory · proposed · Score: 0.90

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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