| Gene Symbol | MBD1 |
| Full Name | Methyl-CpG Binding Domain Protein 1 |
| Aliases | MBD1, CECR2, DKFZp586K0918 |
| Chromosome | 18q21.1 |
| Protein Family | MBD family (Methyl-CpG binding domain family) |
| Function | is a critical epigenetic regulator that binds to methylated CpG dinucleotides in DNA and recruits chromatin remodeling complexes to silence gene expression. |
| Primary Expression | Brain (high), testis, ovary; ubiquitous |
| Subcellular Localization | Nucleus, chromatin |
| Molecular Weight | ~70 kDa (605 amino acids) |
| Amino Acids | 605 aa |
| Exons | 17 |
| Pathways | Dna Methylation, epigenetic regulation |
| UniProt ID | Q9P273 |
| NCBI Gene ID | 4153 |
| Ensembl ID | ENSG00000141644 |
| OMIM | 156311 |
| GeneCards | MBD1 |
| Human Protein Atlas | MBD1 |
| Associated Diseases | neurodegeneration |
| Interactions | FOS, SDHB, C-FOS, VHL, EZH2 |
| KG Connections | 10 knowledge graph edges |
| Databases | GeneCardsHPASTRING |