SDHB

Understanding Entity Pages

This page aggregates everything SciDEX knows about SDHB: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

SDHB is a gene implicated in neurodegeneration research. Key relationships include: interacts with, associated with, activates. Associated with Aging, Als, Alzheimer. Connected to 35 entities in the SciDEX knowledge graph.

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graph TD
    SDHB["<b>SDHB</b>"]
    Alzheimer{"Alzheimer"}
    SDHB -->|"interacts with"| Alzheimer
    Aging{"Aging"}
    SDHB -->|"interacts with"| Aging
    Als{"Als"}
    SDHB -->|"interacts with"| Als
    Huntington{"Huntington"}
    SDHB -->|"interacts with"| Huntington
    Parkinson{"Parkinson"}
    SDHB -->|"interacts with"| Parkinson
    Ms{"Ms"}
    SDHB -->|"interacts with"| Ms
    SDHB -->|"activates"| Als
    Dna_Methylation(["Dna Methylation"])
    SDHB -->|"associated with"| Dna_Methylation
    Complement(["Complement"])
    SDHB -->|"associated with"| Complement
    PPARG["PPARG"]
    SDHB -->|"interacts with"| PPARG
    PARK7["PARK7"]
    SDHB -->|"interacts with"| PARK7
    AMPK["AMPK"]
    SDHB -->|"interacts with"| AMPK
    STX17["STX17"]
    STX17 -->|"associated with"| SDHB
    ATP5MC1["ATP5MC1"]
    ATP5MC1 -->|"regulates"| SDHB
    TXNRD1["TXNRD1"]
    TXNRD1 -->|"regulates"| SDHB
    MFN2["MFN2"]
    MFN2 -->|"regulates"| SDHB
    MITOCHONDRIAL_DYSFUNCTION["MITOCHONDRIAL DYSFUNCTION"]
    MITOCHONDRIAL_DYSFUNCTION -->|"associated with"| SDHB
    UNG["UNG"]
    UNG -->|"associated with"| SDHB
    AGING["AGING"]
    AGING -->|"interacts with"| SDHB
    NEURODEGENERATIVE_DISEASES["NEURODEGENERATIVE DISEASES"]
    NEURODEGENERATIVE_DISEASES -->|"interacts with"| SDHB
    SIRT3["SIRT3"]
    SIRT3 -->|"interacts with"| SDHB
    PGC1A["PGC1A"]
    PGC1A -->|"interacts with"| SDHB
    ATP5F1["ATP5F1"]
    ATP5F1 -->|"interacts with"| SDHB
    P53["P53"]
    P53 -->|"interacts with"| SDHB
    style SDHB fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0