redirect 579 words KG: MGLUR5 2026-03-29
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Contents

mGluR5 Protein

🔬 Protein Info
Gene SymbolMGLUR5
Protein TypeReceptor
FunctionmGluR5 is a Group I metabotropic glutamate receptor that activates PLC signaling and plays roles in learning, memory, and pain perception.
Molecular Weight127 kDa
GeneCardsMGLUR5
Human Protein AtlasMGLUR5
Associated DiseasesEpilepsy
KG Connections34 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (6)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
Astroglial Gap Junction Coordination via Connexin-43 Phospho
Score: 0.50
Sphingomyelin Synthase Activators for Raft Remodeling
Score: 0.47
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42

Related Analyses (8)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (6)

mGluR1 Protein
protein · KG edge: associated_with
CD68 Gene
gene · KG edge: associated_with
ADORA2B Gene
gene · KG edge: downregulates
astrocyte-neuron-metabolic-coupling-parkinsons
general · KG edge: associated_with
Microglia in Neurodegeneration
entity · KG edge: associated_with

Knowledge Graph (12 edges)

MGLUR5 associated_with P2RY2
MGLUR5 regulates MGLUR1
MGLUR5 associated_with CD68
MGLUR5 associated_with P2RY1
MGLUR5 associated_with EPILEPSY
MGLUR5 associated_with PER
MGLUR5 regulates AND
MGLUR5 associated_with ASTROCYTES
MGLUR5 associated_with Epilepsy
MGLUR5 expressed_in Astrocyte