gene 2,602 words KG: P2RY2
Contents

P2RY2 (Purinergic Receptor P2Y2)

🧬 Gene Info
Gene SymbolP2RY2
Full NamePurinergic Receptor P2Y2
Chromosome11
Protein FamilyP2Y receptor family (GPCR)
Protein TypeReceptor
Functionis a unique member of the P2Y receptor family because it is activated by both ATP and UTP with similar potency, making it a central sensor of cellular stress and tissue damage.
Molecular Weight43 kDa
Exons2
UniProt IDQ9ULL8
NCBI Gene ID5029
Ensembl IDENSG00000165326
OMIM173415
GeneCardsP2RY2
Human Protein AtlasP2RY2
Genomic Location11q13.2
Associated DiseasesEpilepsy
KG Connections67 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (5)

Purinergic Signaling Polarization Control
Score: 0.55
Microglial Purinergic Reprogramming
Score: 0.48
Purinergic P2Y12 Inverse Agonist Therapy
Score: 0.48
Gap Junction Hemichannel Modulation for Controlled Mitochond
Score: 0.39
Synaptic Vesicle Tau Capture Inhibition
Score: 0.34

Related Analyses (4)

4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
Synaptic pruning by microglia in early AD
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

mGluR5 Protein
protein · KG edge: associated_with
mGluR1 Protein
protein · KG edge: associated_with
P2RY1 Gene
gene · KG edge: associated_with
P2RX7 Gene
gene · KG edge: regulates
P2RX3 Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

P2RY2 regulates FOXP3
P2RY2 regulates TPH2
P2RY2 regulates CCL3
P2RY2 associated_with P2RY1
P2RY2 associated_with MGLUR1
P2RY2 associated_with CD68
P2RY2 regulates MGLUR1
P2RY2 regulates MGLUR5
P2RY2 associated_with MGLUR5
P2RY2 regulates epilepsy