protein 2,374 words KG: NOTCH2PROTEIN 2026-03-27
kind:proteinsection:proteinsstate:published
Contents

Notch2 Protein

🔬 Protein Info
Gene SymbolNOTCH2
Full NameNotch Receptor 2
Chromosome1p11
Protein TypeReceptor
Functionencodes a highly conserved transmembrane protein that serves as a critical regulator of cell fate decisions, tissue homeostasis, and developmental processes throughout the nervous and vascular syst...
Primary ExpressionCerebral cortex, Hippocampus, Vascular smooth muscle
Subcellular Localization</strong></td><td>Cell membrane, Nucleus</td></tr>
Molecular Weight265 kDa
PathwaysPathway: An Overview, NOTCH, Notch, Notch Signaling
UniProt IDQ12983
NCBI Gene ID4853
Ensembl IDENSG00000134250
OMIM600275
GeneCardsNOTCH2
Human Protein AtlasNOTCH2
Associated DiseasesDiabetes, Glioblastoma
InteractionsLRP1, DLL4, NFKBIE, CDKN2A, SMARCA4, GJA1
KG Connections212 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph