protein 563 words KG: NOX2PROTEIN 2026-03-19
kind:proteinsection:proteinsstate:published
Contents

NADPH Oxidase 2

🔬 Protein Info
Gene SymbolNOX2PROTEIN
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionvarious tissues including the brain and plays roles in neuronal function and disease mechanisms
Subcellular Localization| Phagosome, Cell membrane ! Protein Family | NADPH oxidase family </div> ## Ov
GeneCardsNOX2PROTEIN
Human Protein AtlasNOX2PROTEIN
Associated DiseasesAlzheimer, Parkinson, Traumatic Brain Injury
Known Drugs/Compoundslevodopa
InteractionsAKT, GFAP, SRC, TLR4, TNF, EXOSOMES
KG Connections182 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (5)

Metabolic Reprogramming via Microglial Glycolysis Inhibition
Score: 0.39
Matrix Stiffness Normalization via Targeted Lysyl Oxidase In
Score: 0.51
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.35

Related Analyses (8)

Synaptic pruning by microglia in early AD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (13)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40
Neural Oscillation Dysfunction Validation in Parkinson's Dis
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in