| Gene Symbol | NRXN2 |
| Full Name | Neurexin 2 |
| Chromosome | 11q13.2 |
| Protein Family | Neurexin family (NRXN1, NRXN2, NRXN3) |
| Function | encodes a presynaptic cell adhesion molecule essential for synaptic transmission. |
| Subcellular Localization | Presynaptic membrane, synaptic vesicles |
| Molecular Weight | ~180 kDa (alpha isoform), ~150 kDa (beta isoform) |
| UniProt ID | Q9UHG0 |
| NCBI Gene ID | 9379 |
| Ensembl ID | ENSG00000110076 |
| GeneCards | NRXN2 |
| Human Protein Atlas | NRXN2 |
| Protein Name | Neurexin 2 |
| Brain Region | Expression Level |
| Cerebral [Cortex](/brain-regions/cortex) | High - particularly layer 2/3 pyramidal neurons |
| Associated Diseases | ALS, Alzheimer |
| Interactions | NPTX2, NLGN1, CTSB, CTSD, NRXN3, NRXN1 |
| KG Connections | 44 knowledge graph edges |
| Databases | GeneCardsHPASTRING |