CTSS

Understanding Entity Pages

This page aggregates everything SciDEX knows about CTSS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CTSS is a gene implicated in neurodegeneration research. Key relationships include: activates, inhibits, regulates. Associated with Aging, Alzheimer, Inflammation. Connected to 38 entities in the SciDEX knowledge graph.

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graph TD
    CTSS["<b>CTSS</b>"]
    Inflammation{"Inflammation"}
    CTSS -->|"activates"| Inflammation
    Ms{"Ms"}
    CTSS -->|"inhibits"| Ms
    Alzheimer{"Alzheimer"}
    CTSS -->|"activates"| Alzheimer
    Aging{"Aging"}
    CTSS -->|"regulates"| Aging
    Neuroinflammation{"Neuroinflammation"}
    CTSS -->|"regulates"| Neuroinflammation
    CTSS -->|"regulates"| Inflammation
    AHR["AHR"]
    CTSS -->|"inhibits"| AHR
    CTSD["CTSD"]
    CTSS -->|"inhibits"| CTSD
    LAMP2["LAMP2"]
    CTSS -->|"inhibits"| LAMP2
    Autophagy(["Autophagy"])
    CTSS -->|"inhibits"| Autophagy
    CYTOKINES["CYTOKINES"]
    CTSS -->|"inhibits"| CYTOKINES
    INFLAMMATION["INFLAMMATION"]
    CTSS -->|"activates"| INFLAMMATION
    AGING["AGING"]
    AGING -->|"regulates"| CTSS
    CTSB["CTSB"]
    CTSB -->|"activates"| CTSS
    MICROGLIA_ACTIVATION["MICROGLIA ACTIVATION"]
    MICROGLIA_ACTIVATION -->|"activates"| CTSS
    MICROGLIA["MICROGLIA"]
    MICROGLIA -->|"activates"| CTSS
    CTSL["CTSL"]
    CTSL -->|"activates"| CTSS
    style CTSS fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0