protein 800 words KG: STMN2PROTEIN 2026-03-23
kind:proteinsection:proteinsstate:published
Contents

Stathmin-2 Protein

🔬 Protein Info
Gene SymbolSTMN2
Full NameStathmin-2
Chromosome8q21.13
Protein TypeProtein
FunctionLike other stathmin family members, it can sequester tubulin dimers, reducing the pool of free tubulin available for microtubule polymerization.
Primary ExpressionMotor Neurons, Cortical Neurons, Sensory Neurons, Developing CNS
Molecular Weight20 kDa
PathwaysAxonal Regeneration
UniProt IDSearch UniProt
Ensembl IDENSG00000104435
GeneCardsSTMN2
Human Protein AtlasSTMN2
Associated DiseasesALS, NEURODEGENERATION, frontotemporal dementia
InteractionsTDP-43, SMN, Rb, UNC13A, ALS, NEURODEGENERATIVE DISEASES
SciDEX HypothesesSTMN2 Restoration as a Prerequisite for Axon Growt
KG Connections124 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (5)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Cryptic Exon Silencing Restoration
Score: 0.46
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.35

Related Analyses (7)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
Wnt/β-Catenin Signaling Pathway in Neurodegeneration
mechanism · Pages share 3 hypotheses
WNK1-Bilirubin Signaling in Neuroinflammation and Neuro
mechanism · Pages share 3 hypotheses
vip-vasoactive-intestinal-peptide-signaling-neurodegene
mechanism · Pages share 3 hypotheses
VEGF Signaling and Cerebral Angiogenesis in Neurodegene
mechanism · Pages share 3 hypotheses