| Gene Symbol | SYK |
| Aliases | SYKPROTEIN |
| Chromosome | 9q22 |
| Protein Family | Src family tyrosine kinases |
| Protein Type | Receptor |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | brain microglia (Iba1+ cells) - Increased expression in disease states - Localizes to amyloid plaques in AD |
| Subcellular Localization | </strong></td><td>Cytoplasm, membrane</td></tr> |
| Molecular Weight | 72 kDa |
| Amino Acids | 629 aa |
| Exons | 18 |
| Pathways | PI3K, MAPK |
| UniProt ID | P43405 |
| NCBI Gene ID | 6715 |
| GeneCards | SYK |
| Human Protein Atlas | SYK |
| Associated Diseases | ALS, Alzheimer, CYTOKINES, PYROPTOSIS |
| Known Drugs/Compounds | Entospletinib, metformin, Pustulan, R406 |
| Interactions | AIM2, AKT, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, AND |
| SciDEX Hypotheses | Selective SYK Inhibition for Neuroprotective Micro |
| KG Connections | 375 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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