| Gene Symbol | TCF4 |
| Full Name | Transcription Factor 4 |
| Chromosome | 18q21.2 |
| Protein Type | Transcription Factor |
| Function | TCF4 is a basic helix-loop-helix (bHLH) transcription factor that plays critical roles in neurodevelopment, synaptic plasticity, and neuronal differentiation. |
| Primary Expression | neuronal progenitor cells and post-mitotic neurons |
| Subcellular Localization | </th><td>Nucleus</td></tr> |
| Molecular Weight | 67 kDa |
| Amino Acids | 010 aa |
| Exons | 20 |
| Pathways | Microrna, Wnt, Wnt signaling, autophagy pathway |
| UniProt ID | Q9UJL9 |
| NCBI Gene ID | 6981 |
| Ensembl ID | ENSG00000196628 |
| OMIM | 604275 |
| GeneCards | TCF4 |
| Human Protein Atlas | TCF4 |
| Associated Diseases | Cancer, Carcinoma, Fuchs Endothelial Corneal Dystrophy, Pitt-Hopkins Syndrome, psychiatric disorders, schizophrenia |
| Known Drugs/Compounds | rapamycin |
| Interactions | MYC, FOXP3, MMP9, LAMP1, RAB7A, TCF7L2 |
| KG Connections | 159 knowledge graph edges |
| Databases | GeneCardsHPASTRING |