| Gene Symbol | TYROBP |
| Aliases | DAP12 |
| Chromosome | 19q13.12 |
| Protein Family | ITAM-containing adaptors |
| Protein Type | Adaptor Protein |
| Function | is a transmembrane signaling adaptor protein that plays critical roles in innate immunity and microglial function in the central nervous system. |
| Primary Expression | Microglia, Monocytes, NK cells, Osteoclasts |
| Subcellular Localization | Cell membrane |
| Molecular Weight | ~12 kDa |
| Amino Acids | 113 aa |
| Pathways | Innate Immunity |
| UniProt ID | Q9Y258 |
| NCBI Gene ID | 7305 |
| Ensembl ID | ENSG00000111653 |
| OMIM | 605712 |
| GeneCards | TYROBP |
| Human Protein Atlas | TYROBP |
| Associated Diseases | ALS, ALZHEIMER'S DISEASE, Aging, Alzheimer |
| Known Drugs/Compounds | BERBERINE |
| Interactions | RANK, OVERVIEW, TREM2, DAP12, APOE, SPI1 |
| KG Connections | 383 knowledge graph edges |
| Databases | GeneCardsHPASTRING |