| Gene Symbol | ZCWPW1 |
| Full Name | Zinc Finger CW-Type and PWWP Domain Containing 1 |
| Aliases | Zinc Finger CW-Type and PWWP Domain |
| Chromosome | 5. |
| Function | ZCWPW1 is a 541 amino acid protein containing CW-type and PWWP domains, which are known to bind to modified histones and participate in chromatin remodeling and gene regulation.[2] |
| Primary Expression | Moderate expression in brain and peripheral tissues |
| Molecular Weight | 61 kDa |
| Amino Acids | 541 aa |
| UniProt ID | ZCWPW1 |
| Ensembl ID | ENSG00000060337 |
| GeneCards | ZCWPW1 |
| Human Protein Atlas | ZCWPW1 |
| C9orf72 | Associated with frontotemporal dementia and ALS; ZCWPW1 risk variants show genetic interaction |
| Chromatin remodeling complexes | Cellular machinery with which ZCWPW1 functionally interacts |
| Frontotemporal dementia | Primary neurodegenerative condition linked to ZCWPW1 variants |
| Associated Diseases | ALS, Alzheimer, Atherosclerosis, Dementia, Macular Degeneration |
| Interactions | FERMT2, CELF1, ABCA7, CASS4, EPHA1, CLU |
| KG Connections | 150 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |