gene 824 words KG: RAB12
Contents

RAB12 Gene

🧬 Gene Info
Gene SymbolRAB12
Full NameRAB12, Member RAS Oncogene Family
Chromosome18p11.22
FunctionRAB12 encodes a member of the RAB family of small GTPases, which are key regulators of intracellular vesicle trafficking.
Primary Expressionthe substantia nigra, and dysregulated RAB12 function may contribute to:
Molecular Weight24 kDa
PathwaysmTOR, mtor
UniProt IDQ96CM8
NCBI Gene ID157556
Ensembl IDENSG00000139433
GeneCardsRAB12
Human Protein AtlasRAB12
Associated Diseasesneurodegeneration
InteractionsJIP4, LRRK2, RAB10
SciDEX HypothesesRab12 may better report chronic lysosomal stress b
KG Connections14 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

Rab12 may better report chronic lysosomal stress biology tha
Score: 0.67

Knowledge Graph (12 edges)

LRRK2 interacts_with RAB12
RAB10 interacts_with RAB12
JIP4 interacts_with RAB12
JIP4 activates RAB12
LRRK2 activates RAB12
RAB10 activates RAB12
LRRK2 regulates RAB12
RAB12 regulates ALS
RAB12 phosphorylates Parkinson
RAB12 expressed_in Astrocyte

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.