| Gene Symbol | SCN4B |
| Full Name | Sodium Voltage-Gated Channel Beta Subunit 4 |
| Aliases | Page for SCN4B Gene, Page for SCN4B Protein |
| Chromosome | 11q23.3 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | Brain, Heart, Skeletal muscle |
| Molecular Weight | 25 kDa |
| Amino Acids | 228 aa |
| Exons | 6 |
| UniProt ID | Q9H5Q3 |
| GeneCards | SCN4B |
| Human Protein Atlas | SCN4B |
| Brain | Highest expression in hippocampus, cerebral cortex, and cerebellum. Expressed in both excitatory neurons and inhibitory interneurons. |
| Heart | Strong expression in cardiac myocytes, where it modulates cardiac sodium current (INa). |
| Skeletal Muscle | Present in muscle fibers, contributing to neuromuscular excitability. |
| Associated Diseases | neurodegeneration |
| Interactions | ADCYAP1R1, ATP1A2, CANCER, CLDN4, GENES, NTRK2 |
| KG Connections | 35 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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