gene 1,072 words KG: SETDB1
Contents

SETDB1

🧬 Gene Info
Gene SymbolSETDB1
Full NameSET Domain Bifurcated Histone Lysine Methyltransferase 1
Chromosome1q21.3
Protein TypeTransferase
Functionencodes a histone H3 lysine 9 (H3K9) methyltransferase that catalyzes mono-, di-, and trimethylation of H3K9.
UniProt IDQ15047
Ensembl IDENSG00000143379
OMIM604396
GeneCardsSETDB1
Human Protein AtlasSETDB1
Associated DiseasesLeukemia
InteractionsAND, CGAS-STING
KG Connections11 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (11 edges)

SETDB1 associated_with Leukemia
SETDB1 associated_with Proteasome
SETDB1 associated_with Epigenetic
CANCER therapeutic_target SETDB1
SETDB1 therapeutic_target Cancer
DNA associated_with SETDB1
SETDB1 inhibits Infection
SETDB1 activates CGAS-STING
SETDB1 regulates Stem Cell
SETDB1 expressed_in Macrophage

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