gene 1,092 words KG: SORCS1
Contents

SORCS1 Gene

🧬 Gene Info
Gene SymbolSORCS1
Full NameSortilin-Related VPS10 Domain Containing Receptor 1
Chromosome10q25.3
Protein TypeReceptor
FunctionSORCS1 encodes a member of the sortilin family of VPS10P domain receptors.
Primary Expressionthe brain that participates in intracellular protein trafficking and signaling
Subcellular Localization**BACE1 interaction** - Affects β-secretase processing of APP
Molecular Weight116 kDa
Amino Acids600 aa
PathwaysNeurogenesis
UniProt IDQ9Y6J0
NCBI Gene ID22998
Ensembl IDENSG00000146433
OMIM606283
GeneCardsSORCS1
Human Protein AtlasSORCS1
Associated DiseasesAls, Alzheimer, Bipolar, Coronary Artery Disease, Diabetes
KG Connections52 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

SORLA associated_with SORCS1
SORCS1 implicated_in APP
SORCS1 associated_with SORCS2
SORCS1 associated_with SORLA
SORCS1 associated_with SORCS3
SORL1 regulates SORCS1
SORCS1 regulates SORCS2
SORCS1 regulates BDNF
SORCS1 regulates SORCS3
SORCS1 regulates SORL1

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.