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therapeutic 2,706 words KG: ent-gene-16cf4081
Contents

CSF-1R Inhibitors

🔬 Protein Info
Gene SymbolCSF
Full Name1R Inhibitors
Chromosome5q33.2.
GeneCardsCSF
Human Protein AtlasCSF
Associated DiseasesMULTIPLE SCLEROSIS
Known Drugs/CompoundsADUCANUMAB
KG Connections134 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

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🌐 Cross-references

Wikipedia

Related Hypotheses (7)

TREM2-mediated microglial tau clearance enhancement
Score: 0.62TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75APOE-TREM2 Interaction Modulation
Score: 0.74TREM2-Dependent Microglial Senescence Transition
Score: 0.62TREM2-Mediated Selective Aggregate Clearance Pathway
Score: 0.58

Related Analyses (7)

Synaptic pruning by microglia in early AD
neurodegeneration · completedExtracellular vesicle biomarkers for early AD detection
neurodegeneration · archivedNeuroinflammation and microglial priming in early Alzheimer'
neurodegeneration · archivedSynaptic pruning by microglia in early AD
neurodegeneration · archivedTau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

Related Experiments (30)

FLS Stimulation and Transcriptomic Analysis
exploratory · completed · Score: 0.95iPSC-derived endothelial cell iron uptake with RLS CSF expos
exploratory · proposed · Score: 0.90CSF Dynamic Biomarkers for Differential Diagnosis of NPH vs
clinical · proposed · Score: 0.90CSF iron content analysis in RLS patients versus controls
clinical · proposed · Score: 0.85Alpha-Synuclein Seed Amplification Assay Validation
clinical · proposed · Score: 0.40

Key Papers (1)

Assessment of the Spatial Distribution of Moisture Content in Granular
Sensors (Basel, Switzerland) 2024

Knowledge Graph (5 edges)

h-a512eecb08 targets ent-gene-16cf4081
39891235 is required for ent-gene-16cf4081
ent-gene-16cf4081 targeted_by h-a512eecb08
h-3685e352 targets ent-gene-16cf4081
ent-gene-16cf4081 targeted_by h-3685e352

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