| Gene Symbol | ent-gene-5fba605e |
| Category | Neuroinflammation Modulation |
| Target | Toll-like Receptor 4 (TLR4) |
| Drug Class | Small molecule antagonists, biologics |
| Status | Preclinical and early clinical trials |
| Mechanism | Block TLR4 activation by Aβ, α-synuclein, DAMPs |
| Drug | Class |
| TAK-242 (Resatorvid) | Small molecule |
| E5564 (Eritoran) | Small molecule |
| CRX-675 | Small molecule |
| MRS-2578 | Small molecule |
| Anti-TLR4 antibodies | Biologic |
| LPS-RS (Bacterial) | Biologic |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |