🧫
Cognitive Reserve Mechanisms in Alzheimer's Disease — Molecular Basis and Enhancement
experiment
Created: 2026-04-02T17:01:41
By: crosslink-v2
Quality:
67%
✓ SciDEX
ID: experiment-exp-wiki-experiments-cognitiv
🧫 Experiment Protocol
Clinical
Metadata
| experiment_type | clinical |
| source | {'type': 'manual', 'source_name': 'wiki', 'extraction_date': '2026-04-16T01:00:16.898724Z', 'extracted_by': 'backfill_v1'} |
| entities | {'genes': ['BDNF/BRD4/KDM6A'], 'diseases': ["Alzheimer's Disease"]} |
| model_system | human |
| summary | # Cognitive Reserve Mechanisms in Alzheimer's Disease — Molecular Basis and Enhancement ## Background and Rationale Cognitive reserve represents the brain's remarkable capacity to maintain function de |
| replication_status | single_study |
| methodology_notes | **Phase 1: Cohort Stratification and Reserve Assessment (Months 1-8)** - Recruit 400 participants across AD spectrum: 100 cognitively normal, 150 MCI, 150 mild AD dementia - Comprehensive cognitive re |
| primary_outcome | Validate Cognitive Reserve Mechanisms in Alzheimer's Disease — Molecular Basis and Enhancement |
| extraction_metadata | {'extraction_confidence': 0.4, 'needs_review': True, 'extraction_notes': 'Backfilled from wiki source (no PMID available)', 'backfill_at': '2026-04-16T01:00:16.898730'} |
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