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Stress granules: Guardians of cellular health and triggers of disease.
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📄 Paper Details
Stress granules: Guardians of cellular health and triggers of disease.
Desai M, Gulati K, Agrawal M, Ghumra S, Sahoo PK
Abstract
Stress granules are membraneless organelles that serve as a protective cellular response to external stressors by sequestering non-translating messenger RNAs (mRNAs) and regulating protein synthesis. Stress granules formation mechanism is conserved across species, from yeast to mammals, and they play a critical role in minimizing cellular damage during stress. Composed of heterogeneous ribonucleoprotein complexes, stress granules are enriched not only in mRNAs but also in noncoding RNAs and vari...
▸Metadata
| doi | 10.4103/NRR.NRR-D-24-01196 |
| pmid | 39995077 |
| year | 2026 |
| pmc_id | None |
| _origin | {'url': 'https://doi.org/10.4103/NRR.NRR-D-24-01196', 'type': 'external', 'tracked_at': '2026-04-23T21:23:15.448815'} |
| authors | ['Desai M', 'Gulati K', 'Agrawal M', 'Ghumra S', 'Sahoo P'] |
| journal | Neural regeneration research |
| _schema_version | 1 |
| quality_scoring | {'quality_status_review': {'status': 'pass', 'signals': ['has_provenance_chain', 'has_metadata'], 'task_id': '3854fa92-f632-4cba-be41-396420da7151', 'rationale': 'quality_status assigned by automated |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
15%
Debates
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Outgoing
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