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TMEM106B

wiki page Created: 2026-04-02 13:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-proteins-tmem106b-protein

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slug	proteins-tmem106b-protein
entity_type	protein
kg_node_id	TMEM106B

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Linked Artifacts (49)

mentions🧫TMEM106B Haplotype as Genetic Modifier in FTD — Mechanism an70%

related🧫TMEM106B Haplotype as Genetic Modifier in FTD — Mechanism an70%

mentions🧪Lysosomal Membrane Repair Enhancement65%

related🧫TMEM106B Haplotype as Genetic Modifier in FTD — Mechanism an63%

see_also📖Amyloid-Related Imaging Abnormalities (ARIA)60%

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see_also📖ABCA1 - ATP-Binding Cassette Transporter A160%

see_also📖ABI3 Gene60%

see_also📖ACE Gene60%

see_also📖adam1760%

see_also📖Packard Center for ALS Research60%

see_also📖Aging vs Neurodegeneration: Mechanistic Comparison Matrix60%

related🧪Lysosomal Membrane Repair Enhancement58%

mentions🧪Cross-Seeding Prevention Strategy50%

mentions🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer50%

mentions🧪APOE4 Allosteric Rescue via Small Molecule Chaperones50%

mentions🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction50%

mentions🧪Targeted APOE4-to-APOE3 Base Editing Therapy50%

mentions🧪Competitive APOE4 Domain Stabilization Peptides50%

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mentions🧪TREM2 Conformational Stabilizers for Synaptic Discrimination50%

mentions🧪TREM2-mediated microglial tau clearance enhancement50%

mentions🧪Cell-Type Specific TREM2 Upregulation in DAM Microglia50%

mentions🧪The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction50%

mentions🧪TFEB-PGC1α Mitochondrial-Lysosomal Decoupling50%

mentions🧪TREM2-Dependent Microglial Senescence Transition50%

mentions🧪Heat Shock Protein 70 Disaggregase Amplification50%

mentions🧪Serine/Arginine-Rich Protein Kinase Modulation50%

mentions🧪Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m50%

related🔬What are the mechanisms underlying rna binding protein dysre50%

related🔬What are the mechanisms underlying mitochondrial transfer be50%

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related🔬What are the mechanisms underlying protein aggregation cross50%

related🔬What are the mechanisms underlying rna binding protein dysre50%

related🔬What are the mechanisms underlying mitochondrial transfer be50%

related🔬Analyze circuit-level changes in neurodegeneration using All50%

related🔬RNA binding protein dysregulation across ALS FTD and AD50%

related🧪APOE-Dependent Autophagy Restoration50%

related🧪APOE-TREM2 Interaction Modulation50%

related🧪TREM2-Mediated Selective Aggregate Clearance Pathway50%

mentions🔬What are the mechanisms underlying protein aggregation cross40%

mentions🔬What are the mechanisms underlying rna binding protein dysre40%

mentions🔬RNA binding protein dysregulation across ALS FTD and AD40%

mentions🔬Analyze circuit-level changes in neurodegeneration using All40%

related🧪Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m40%

related🧪Heat Shock Protein 70 Disaggregase Amplification40%

related🧪Serine/Arginine-Rich Protein Kinase Modulation40%

related🧪Cross-Seeding Prevention Strategy40%

related🔬What are the mechanisms underlying tdp-43 phase separation t30%