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Amyloid tracers detect multiple binding sites in Alzheimer's disease brain tissue.
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ID: paper-23757761
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Amyloid tracers detect multiple binding sites in Alzheimer's disease brain tissue.
["Ni R", "Gillberg P", "Bergfors A", "Marutle A", "Nordberg A"]
Abstract
Imaging fibrillar amyloid-β deposition in the human brain in vivo by positron emission tomography has improved our understanding of the time course of amyloid-β pathology in Alzheimer's disease. The most widely used amyloid-β imaging tracer so far is (11)C-Pittsburgh compound B, a thioflavin derivative but other (11)C- and (18)F-labelled amyloid-β tracers have been studied in patients with Alzheimer's disease and cognitively normal control subjects. However, it has not yet been established wheth...
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