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Mechanisms of electroacupuncture-induced neuroprotection in acute stroke rats: the role of astrocyte-mediated mitochondrial transfer.
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ID: paper-40598228
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Mechanisms of electroacupuncture-induced neuroprotection in acute stroke rats: the role of astrocyte-mediated mitochondrial transfer.
["Guo Y", "Fu T", "Cheng Y", "Li Y", "Zhang R", "Ma Q", "Wang G", "Ning W", "Fan W", "Yang J"]
Abstract
BACKGROUND: Ischemic stroke significantly threatens human health, and current treatments remain limited, necessitating novel strategies. Mitochondrial transfer between neurons represents a crucial endogenous neuroprotective mechanism. OBJECTIVE: This study investigated whether electroacupuncture enhances mitochondrial transfer from astrocytes to damaged neurons during acute cerebral ischemia, promoting neuroprotection. METHODS: A middle cerebral artery occlusion (MCAO) model in Sprague-Dawley (S...
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