Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about alpha-synucleinopathies: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Associated Genes | APOE |
| KG Connections | 8 knowledge graph edges |
| Databases | OMIMOrphanetClinicalTrialsPubMed |
Knowledge base pages for this entity
flowchart TD
alpha_synucleinopathies["alpha-synucleinopathies"]
Alpha_Synuclein(["Alpha-Synuclein"])
SNCA(["SNCA"])
PARKINSON(["PARKINSON"])
Parkinson_s_Disease["Parkinson's Disease"]
disease["disease"]
PARKINSON_S("PARKINSON'S")
SYNUCLEIN("SYNUCLEIN")
alpha_synucleinopathies -->|"associated with"| Alpha_Synuclein
alpha_synucleinopathies -->|"associated with"| SNCA
alpha_synucleinopathies -->|"associated with"| PARKINSON
alpha_synucleinopathies -->|"associated with"| Parkinson_s_Disease
alpha_synucleinopathies -->|"associated with"| disease
alpha_synucleinopathies -->|"associated with"| PARKINSON_S
alpha_synucleinopathies -->|"associated with"| SYNUCLEIN
style alpha_synucleinopathies fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff| Target | Relation | Type | Str |
|---|---|---|---|
| SNCA | associated_with | gene | 0.50 |
| Alpha-Synuclein | associated_with | protein | 0.50 |
| PARKINSON | associated_with | gene | 0.50 |
| Parkinson's Disease | associated_with | disease | 0.50 |
| disease | associated_with | disease | 0.50 |
| PARKINSON'S | associated_with | concept | 0.50 |
| SYNUCLEIN | associated_with | concept | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| APOE | associated_with | gene | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-13 | 0 hypotheses
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||