Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about AMS-17: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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flowchart TD
N0["AMS-17"]
N1["NLRP3"]
N0 -->|"inhibits"| N1
N2["Cognitive Function"]
N0 -->|"associated with"| N2
N3["TNF"]
N0 -->|"downregulates"| N3
N4["IL1B"]
N0 -->|"downregulates"| N4
N5["Tnf-Alpha"]
N0 -->|"downregulates"| N5
N6["Il-1Beta"]
N0 -->|"downregulates"| N6
N7["IL-4"]
N0 -->|"upregulates"| N7
N8["Remyelination"]
N0 -->|"promotes"| N8
classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
classDef drug fill:#1a2a2a,stroke:#26c6da,color:#e0e0e0
classDef cell_type fill:#2a1a2a,stroke:#ab47bc,color:#e0e0e0
classDef phenotype fill:#2a2a1a,stroke:#ffa726,color:#e0e0e0
classDef process fill:#1a2a2a,stroke:#66bb6a,color:#e0e0e0
classDef biological_process fill:#1a2a2a,stroke:#66bb6a,color:#e0e0e0
classDef concept fill:#1a1a2a,stroke:#7986cb,color:#e0e0e0
classDef entity fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef therapeutic fill:#1a2a2a,stroke:#26c6da,color:#e0e0e0
classDef index fill:#1a1a2a,stroke:#7986cb,color:#e0e0e0
class N0 concept
class N1 protein
class N2 phenotype
class N3 protein
class N4 protein
class N5 protein
class N6 protein
class N7 protein
class N8 process| Target | Relation | Type | Str |
|---|---|---|---|
| TNF | downregulates | protein | 0.90 |
| IL1B | downregulates | protein | 0.90 |
| Dementia | treats | disease | 0.85 |
| Neuroinflammation | suppresses | process | 0.85 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||