BACE2

Understanding Entity Pages

This page aggregates everything SciDEX knows about BACE2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

BACE2 is a protein involved in neurodegeneration research. Key relationships include: therapeutic target, treats, implicated in. Associated with Als, Alzheimer. Connected to 10 entities in the SciDEX knowledge graph.

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flowchart TD
    N0["BACE2"]
    N1["Als"]
    N0 -->|"associated with"| N1
    N2["Alzheimer"]
    N0 -->|"therapeutic target"| N2
    N3["BACE1"]
    N0 -->|"treats"| N3
    N4["ALZHEIMER"]
    N0 -->|"therapeutic target"| N4
    N5["PRESENILIN"]
    N0 -->|"therapeutic target"| N5
    N6["AMYLOID"]
    N0 -->|"therapeutic target"| N6
    N7["GENES"]
    N0 -->|"therapeutic target"| N7
    N8["ALZHEIMER'S DISEASE"]
    N0 -->|"therapeutic target"| N8
    N9["APP"]
    N0 -->|"therapeutic target"| N9
    N10["neurodegeneration"]
    N0 -->|"implicated in"| N10

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N1 disease
    class N2 disease
    class N3 gene
    class N4 gene
    class N5 gene
    class N6 gene
    class N7 gene
    class N8 gene
    class N9 gene