gene

CACNB3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CACNB3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

15Connections
0Hypotheses
0Analyses
12Outgoing
3Incoming

Summary

Page for CACNB3

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🧬 Gene Info
Gene SymbolCACNB3
Full NameCACNB3
Protein TypeGene
Functionis a hallmark across AD, PD, and FTD spectra.
Molecular Weight66 kDa
PathwaysMAPK, mapk, PI3K, mTOR
NCBI Gene IDSearch NCBI
GeneCardsCACNB3
Human Protein AtlasCACNB3
Associated DiseasesMesial Temporal Lobe Epilepsy
KG Connections15 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Wiki Pages (4)

Knowledge base pages for this entity

Canonical Page

CACNB3

gene · 679 words

CACNB3 Protein

protein · 1019 words

Proteins

index · 296 words

Genes

index · 271 words

Pathway Diagram

flowchart TD
    N0["CACNB3"]
    N1["Plasma membrane"]
    N0 -->|"associated with"| N1
    N2["Ca(v)1.4"]
    N0 -->|"associated with"| N2
    N3["Kir/Gem"]
    N0 -->|"binds"| N3
    N4["Mesial Temporal Lobe Epilepsy"]
    N0 -->|"associated with"| N4
    N5["Blood-Brain Barrier"]
    N0 -->|"associated with"| N5
    N6["Insulin Expression"]
    N0 -->|"regulates"| N6
    N7["CACNA1C"]
    N0 -->|"participates in"| N7
    N8["hsa-miR-34a-5p"]
    N8 -->|"regulates"| N0
    N9["ADRB1"]
    N0 -->|"associated with"| N9
    N10["AGING"]
    N0 -->|"therapeutic target"| N10
    N11["CPT2"]
    N0 -->|"associated with"| N11
    N12["CPT1A"]
    N0 -->|"associated with"| N12
    N13["CACNA2D2"]
    N0 -->|"associated with"| N13
    N14["Rb"]
    N0 -->|"associated with"| N14

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N2 protein
    class N3 protein
    class N4 disease
    class N7 protein
    class N9 gene
    class N10 gene
    class N11 gene
    class N12 gene
    class N13 gene
    class N14 protein

Outgoing (12)

TargetRelationTypeStr
Plasma membraneassociated_withentity0.90
Ca(v)1.4associated_withprotein0.80
Kir/Gembindsprotein0.80
Mesial Temporal Lobe Epilepsyassociated_withdisease0.80
Insulin Expressionregulatesbiological_process0.80

Incoming (3)

SourceRelationTypeStr
hsa-miR-34a-5pregulatesentity0.70
CDH1therapeutic_targetgene0.60
PERtherapeutic_targetgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found