gene

adrb1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about adrb1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

17Connections
0Hypotheses
0Analyses
11Outgoing
6Incoming

No summary available yet. View on Wiki →

🧬 Gene Info
Gene SymbolADRB1
Full NameBeta-1 Adrenergic Receptor
Chromosome10q25.3
Functionregulator of cardiac and neuronal function
Primary Expressionkey regions involved in cognition, arousal, and autonomic regulation, making it relevant to neurodegenerative diseases including [Alzheimer's disease]
Amino Acids477 aa
UniProt IDP08588
NCBI Gene ID153
Ensembl IDENSG00000143578
OMIM109630
GeneCardsADRB1
Human Protein AtlasADRB1
Associated DiseasesParkinson's disease, Alzheimer's disease
DatabasesGeneCardsHPASTRING
🔮 Predicted Structure: adrb1 — AlphaFold P08588 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (16)

Knowledge base pages for this entity

ADCY3 — Adenylate Cyclase 3

gene · 2825 words

ADRB1 Gene

gene · 1715 words

Solitary Nucleus Neurons

cell · 1449 words

A2 Noradrenergic Neurons

cell · 1410 words

Technical Architecture

scidex_docs · 1216 words

Pathway Diagram

flowchart TD
    N0["ADRB1"]
    N1["AGING"]
    N0 -->|"therapeutic target"| N1
    N2["CPT2"]
    N0 -->|"associated with"| N2
    N3["CPT1A"]
    N0 -->|"associated with"| N3
    N4["CACNA2D2"]
    N0 -->|"associated with"| N4
    N5["Rb"]
    N0 -->|"associated with"| N5
    N6["CDH1"]
    N6 -->|"therapeutic target"| N0
    N7["PER"]
    N7 -->|"therapeutic target"| N0
    N8["CACNB3"]
    N8 -->|"associated with"| N0
    N9["neurodegeneration"]
    N0 -->|"implicated in"| N9

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef therapeutic fill:#1a2a2a,stroke:#26a69a,color:#e0e0e0
    class N1 gene
    class N2 gene
    class N3 gene
    class N4 gene
    class N5 protein
    class N6 gene
    class N7 gene
    class N8 gene

Outgoing (11)

TargetRelationTypeStr
CPT2associated_withgene0.60
CACNA2D2associated_withgene0.60
Rbassociated_withprotein0.60
DBHinteracts_withgene0.60
ERBB4interacts_withgene0.60

Incoming (6)

SourceRelationTypeStr
CACNB3associated_withgene0.60
ADRA1Ainteracts_withgene0.60
ADRA2Ainteracts_withgene0.60
CDH1therapeutic_targetgene0.60
PERtherapeutic_targetgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found